Dr. Girish Chandran
Current Position: Coordinator-Biochemistry, Asst. Professor
Qualification: Ph.D.
Teaching Experience: 8 years
Courses offered: Techniques in Biology, Physiology and Nutrition, Biomolecules, Clinical Biochemistry, Human Physiology, Research Methodology, Biostatistics, Gene Technology, Immunology, Carbohydrate Metabolism, Lipid Metabolism, Enzymology, Biotechnology, Molecular biology, Cell Biology.
Current research interests: Utilizing the drosophila system to study the mechanisms involved in pain, Alzheimer’s and depression pathophysiology separately and scope for therapeutic strategies. The study focuses on understanding behavioural and biochemical evidences of neurodegeneration and neurotherapy.
Doctoral Research: Doctoral work aimed at the assessment of neuromodulatory properties Selaginella delicatulaper se and against experimentally induced neurodegenerative diseases employing rodent and Drosophila models. The work included studying its modulatory efficacy on motor and cognition behaviour in experimentally induced neurotoxicity models. Studies also included analysing cellular targets of Selaginella flavonoids.
Post Doctoral Research: Programmed cell death during the early eye development in dyl mice with Peters’ anomaly. This research work included elucidating the cellular mechanisms involved in the development of lentico-corneal stalk among the developing fetes. This work included techniques like fluorescent imaging, PCR, TUNEL assays etc.
Research Experience: 18 years
Publications:
No. of publications: 9
No. of Papers presented in National/International symposia/conferences: 70(India, Germany-2, South Korea, Austria, USA, Sweden, France, Dubai, Denmark)
- Chandran G., D'Silva RL, Muralidhara (2023). Use of insect model to study Parkinson's disease pathophysiology by inducing GSH-depletion and behavioral deficits among larvae: Evidences of ameliorative properties of phytoconstituents. Movement Disorders, 38 (2), 1262 IF: 8.6
- Book Chapter: Chandran G., and S.R. Ramesh. (2021). Analysis of Drosophila eye pigments by paper and thin layer chromatography. Book: Experiments with Drosophila for Biology Courses. Indian Academy of Sciences, India.
- Book Chapter: Chandran G. (2021). Negative geotaxis or climbing assay for assessment of locomotor function in adult Drosophila. Book: Experiments with Drosophila for Biology Courses. Indian Academy of Sciences, India.
- Book Chapter: Chandran G., Chauhan J.B., Grace S.R., et al., (2019) Fern to Pharma: Potential Neuroameliorative Properties of Pteridophytes. In: Ozturk M., Hakeem K. (Eds) Plant and Human Health, Volume 3. Springer International.
- Book Chapter: Grace S.R., Chandran G., Chauhan J.B., et al., (2019) Terpenoids: An Activator of “Fuel-Sensing Enzyme AMPK” with Special Emphasis on Antidiabetic Activity. In: Ozturk M., Hakeem K. (eds) Plant and Human Health, Volume 2. Springer International.
- Chandran G., and Muralidhara 2016. Biochemical and behavioral evidences for neuromodulatory properties of Selaginella delicatula against 3-nitropropionic acid model in mice. Int J Neurology Research, 2(1): 49-60
- Book Chapter: Chandran G., Lalith KV, Muralidhara, 2015. Biflavonoids: Therapeutic potential of novel flavonoid dimers. In: Govil, J.N. and Pathak, M. eds. Recent Progress in Medicinal Plants Volume 40 – Flavonoids and Antioxidants. Studium Press LLC, U.S.A. pp.316-330.
- Review: Chandran G., and Muralidhara, 2014. Insights on the Neuromodulatory propensity of Selaginella (Sanjeevani) and its potential pharmacological applications. CNS Neurol Dis-Drug Targets, 13, 82-95. IF: 3.2
- Chandran G., and Muralidhara, 2013. Neuroprotective Effect of Aqueous Extract of Selaginella delicatula as Evidenced by Abrogation of Rotenone-Induced Motor Deficits, Oxidative Dysfunctions, and Neurotoxicity in Mice. Cell Mol Neurosci 33(7), 929-942. IF: 3.5
- Chandran G., and Muralidhara 2012. Neuromodulatory potential of Selaginella delicatula aqueous extract against Rotenone induced oxidative dysfunctions and neurotoxicity in Drosophila melanogaster. NeuroToxicology 33(3), 444–456. IF: 3.4
girishchandran.pgc@mahajana.edu.in
0821-4009609